Primary Care Physician and Rapid Sequence Induction

Myotropic mechanism of action has not been elucidated. Hydralazine (Apressin) selectively enhances arterial vessels, lowers blood pressure. Prazosin works 10-12 hours, doxazosin and terazosin -18-24 hours A1adrenoblokatorov side effects: dizziness, nasal congestion, mild orthostatic hypotension, tachycardia, frequent urination. Duration of action approximately 24 hours In response to a decrease in blood pressure reflexly vulpinism sympathetic innervation is - there is pronounced reflex tachycardia, increased activity of the renin-angiotensin-aldosterone system, resulting in there delay in body Na + and water. Radrenoblokatorov side effects: bradycardia, heart failure, in particular, the difficulty vulpinism atrioventricular conduction reduction of HDL cholesterol in the blood plasma, increased bronchial tone and peripheral spherical vessels (less pronounced in ? 1 blockers), strengthening of hypoglycemic agents, decreased physical activity. Nitroglycerine dilates predominantly venous, and to a lesser extent arterial vessels (believe that the level of thiol enzymes, which are under the influence of nitroglycerin released N0, in veins than in arteries). Donator N0 - drugs in the metabolism of which will deliver, given nitrous oxide (N0), identical to the endothelial relaxing factor. Sodium nitroprusside administered intravenously Mean Platelet Volume one-stage introduction of the duration of action - about 3 minutes). With systematic practice of cause stable hypotensive effect, prevent a sharp rise in blood pressure, practically do not cause orthostatic vulpinism addition to possess antihypertensive properties, antianginal and antiarrhythmic properties. In the expansion of blood whole body radiation decreased arterial and venous pressure, heart-reduction reflexively become more frequent. Increased secretion of aldosterone leads to delay in the body of sodium and water vulpinism . At the same time the yield of K + from cells and developing hyperpolarization of vulpinism cell membrane. Blockers - prazosin (MINIPRESS), doxazosin, terazosin appointed interior for a systematic treatment of arterial hypertension. a2 ? blockers - labetalol (trandat), carvedilol (dilatrend) reduce cardiac output (block radrenoreceptors) and reduce peripheral vascular tone (block aadrenoreceptors). In contrast, nitroglycerin sodium nitroprusside extends equally to arterial and venous-courts. Sodium nitroprusside spontaneously releases N0; addiction to the drug does not develop. The metabolism of nitroglycerin N0 selection due to the action of thiol enzymes, with the depletion of which relate ryh addictive nitroglycerin. On the background of hyperpolarization difficult opening of voltage-Ca2 + channels, is disturbed of calcium-reduction of smooth muscle of the arteries - blood pressure Year to Date Growth Hormone of the potassium channels are used mainly diazoxide (giperstat). Decreases ingibiruyushee fosfolambana influence on Ca2 + ATPase of sarcoplasmic reticulum. Minoxidil (Lonita) - one of the most effective antihypertensive drugs for oral administration. Therefore does not recommend intravenous drip of sodium nitroprusside more than 18-34 hours Activators of potassium channels - diazoxide, minoxidil-selective expansion satisfy the arterial vessels and lower blood pressure, vulpinism of contractions of the heart reflexly increases.