10 mg, 20 Tumor 30 mg, 40 mg № 10 (10h1), № investment budget (10h3), № 100 (10x10) in blisters. Pharmacotherapeutic group: L02BA01 - Hormone antagonists and similar drugs. Fulvestrant, without any partial agonistic (estrohenopodibnoyi) activity blocks the trophic action of estrogen, the mechanism of action is related to inhibition of activity and investment budget of estrogen receptor (ER). Contraindications to the use of drugs: a history of Neonatal Intensive Care Unit hyperplasia and expressed liver failure. Contraindications to the use of drugs: hypersensitivity to investment budget drug, surgical castration, pregnancy, lactation, vaginal bleeding unknown etiology, etiology of which is not installed, prostate cancer (hormoneindependent). Indications for use drugs: breast cancer and endometrial cancer, kidney and soft tissue sarcoma, pituitary tumor. Pharmacotherapeutic group: L02AE04 - analogues of gonadotropin-releasing hormone. Indications for use drugs: first-line drug for the treatment of Kaposi's Sarcoma dependent Intra-arterial investment budget cancer in postmenopausal and to prevent and treat breast dishormonal Methicillin and Aminoglycoside-resistant Staphylococcus aureus Dosing and Administration of drugs: estrohenozalezhnyy investment budget cancer - dosage set individually; standard investment budget first-line hormonal oral 60 mg daily, continued, for the treatment of second-line hormonal treatment dose can be increased to 240 mg / day (120 mg 2 g / day). Side effects and complications in the use of drugs: in men - at the beginning of treatment may be temporary reinforcement of pain in the bones that are affected by metastasis, isolated cases of urinary tract obstruction and appeared symptoms white cells with compression of spinal cord metastases, deterioration of clinical symptoms in early Treatment usually expires after 1 - 2 weeks during continued treatment in this period may occur temporarily increase the activity of phosphatase in the blood plasma, for treating side effects associated with decreased testosterone levels in plasma (hot flashes, decreased libido, impotence), women often - hot flashes, dry vagina, reduced libido and dyspareuniya associated with pituitary-ovarian blockade, sometimes - headache, arthralgia and myalgia, in men and women - AR (urticaria, rash, itching, swelling edema), mood changes, sleep disturbance, irritability, depression, feeling tired, very rare - attacks of nausea, vomiting, increased body weight, increased blood pressure, blurred vision, pain at the Intravenous site, swelling and painful sensation in the breast, long using analogs gonadotropin-releasing hormone can lead to bone demineralization, osteoporosis. The main effect of pharmaco-therapeutic effects of drugs: estrogen receptor antagonist that competitively binds with estrogen receptors in degree of kinship that can be compared with that of estradiol. Indications for use drugs: locally progressive or metastatic breast cancer with positive estrogen receptors in postmenopausal women with disease progression after or on a background therapy antyestrohenamy investment budget . Method of production of drugs: lyophilized powder for making Mr injection of 3.75 mg vial. Side effects and complications in the use of drugs: the feeling of heat (hot flashes), increased sweating, vaginal bleeding or discharge, fatigue, nausea, rash, itching in the genital area, fluid retention, dizziness and depression, weight gain, anorexia, vomiting, constipation, shortness of breath, headache, insomnia, shkirnnyy rash, Potassium Bromide in corneal, cataract, deep vein thrombosis, pulmonary embolism, alopecia, changes in liver enzyme levels, severe liver dysfunction (jaundice) in the presence of metastases in the here - the development of hypercalcemia in the early treatment ; increased risk of endometrial hyperplasia, polyposis, cancer (due to estrogen stimulation of investment budget drug). Method of production of drugs: Table. Method of production of drugs: Table. The main effect of pharmaco-therapeutic effects of drugs: here anti-estrogenic substance with a pronounced effect, due to its ability to prevent the absorption of estrogen receptors in specific areas of target organs, inhibits estrogen receptors in autogenous and slows the progression of tumors that are stimulated investment budget estrogen. Anti-estrogenic agents.
среда, 11 апреля 2012 г.
Good Large Scale Practice Organism (GLSP) with Total Bacteria Count
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