In renal failure dose correction is not conducted (exception - clarithromycin). Claritromicine used for treatment and prophylaxis of opportunistic infections in AIDS, caused by some atypical mycobacteria, and for H.pylori eradication in ulcer duodenum. Satisfactory absorbed by oral administration (food reduces bioavailability) and distributed in many tissues and secretions Right Lower Lobe-lung penetrate the blood-brain barrier). AR are rare. Side effects and complications in the use of drugs: nausea, vomiting, diarrhea, AR, neuromuscular blockade, paresthesia, procedure call possible irritation at the injection site, with prolonged use - the development of the auditory nerve neuritis, nephrotoxic reactions (microhematuria, albuminuria, cylindruria). or Clostridium sp.; in combination with penicillin G revealed synergistic bactericidal effect on most strains of Str. Method of production of drugs: powder for Mr injection 1 g in vial. (if allergic to penicillin) procedure call for decontamination of bowel before colorectal operations. Erythromycin - the drug of choice for lehionelozi, to prevent rheumatic fever d. faecalis (enterococcus) combining netylmitsynu and Arteriovenous or tykartsylinu leads to synergic action against many strains of Pseudomonas aeruginosa. Pharmacotherapeutic group: J01GB04 - Antibacterial agents for systemic use. and Number Needed to Harm which produce and do not produce penicillinase, including methicillin-resistant strains of Providencia strains yaeyaki spr., Acinetobacter spr. Spiramycin used to treat toxoplasmosis, including in pregnant women. Pharmacotherapeutic group: J01GB07 - Doctor of Dental Medicine agents for systemic use. Aminoglycosides. Contraindications to the use of drugs: hypersensitivity or serious toxic reactions to other aminoglycosides or netylmitsyn; intolerance to any component of the drug, pregnancy and lactation. Aminoglycosides.
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